Primer and probe synthesis

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DIA-UP BIO has advanced automated production equipment and quality testing equipment, which can meet the requirements of different customers for large-scale and high-throughput synthesis of products. It adopts the commercial industrial production process of oligoglycosides and strictly controls the entire production process according to the ISO13485:2016 quality management system, ensuring stable and high-quality primer and probe synthesis services for customers.

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Product Type	Modifier Type	Product Type	Modifier Type
Single label probe class	LNA(bp)	Double labeled probes	5′ FAM 3′ TAMRA
	DI(bp)		5′ FAM 3′ BHQ1
	DU(bp)		5′ FAM 3′ Dabcy1
	Thio substitution(bp)		5′ FAM 3′ MGB
	Spacer C3(bp)		5′ FAM 3′ Eclipse
	Spacer 9(bp)		5′ HEX 3′ BHQ1
	Spacer 12(bp)		5′ HEX 3′ TAMRA
	Spacer 18(bp)		5′ HEX 3′ Eclipse
	dSpacer		5′ HEX 3′ Dabcy1
	dT-C6-Amino		5′ HEX 3′ MGB
	5′ -sulfydryl		5′ ROX 3′ BHQ2
	5′ NH2 C6		5′ ROX 3′ MGB
	NH2 C12		5′ Cy5 3′ BHQ2
	3′ NH2 C7		5′ Cy5 3′ BHQ3
	5′ -Phosphorylation		5′ Cy5 3′ MGB
	3′ -Phosphorylation		5′ Cy5.5 3′ BHQ3
	5′ Biotin		5′ TET 3′ BHQ1
	3′ Biotin		5′ TET 3′ TAMRA
	5′ FAM		5′ VIC 3′ Dabcy1
	3′ FAM		5′ VIC 3′ BHQ1
	5′ HEX		5′ VIC 3′ TAMRA
	5′ TET		5′ VIC 3′ MGB
	5′ TAMRA	Middle dt marker class	dT-FAM
	3′ TAMRA		dT-ROX
	5′ ROX		dT-TAMRA
	3′ ROX		dT-Dabcy1
	5′ Cy3		dT-Cy3
	3′ Cy3		dT-Cy5
	5′ Cy5	Single label probe class	3′ -Dabcy1
	Cy5.5		5′ -Dabcy1
	3′ Cy5		3′ BHQ1
	5′ VIC		3′ BHQ2
	3′ddA/ddT/ddC/ddG		3′ BHQ3
	5′rapp		3′ eclipse
			3′ -MGB

1. Strict quality standards: QC testing items cover five aspects: appearance, quantification, molecular weight, purity, fluorescence excitation/emission wavelength, etc;

2. Industrial production customization: can provide high purity primers and ultra pure primers exclusive to large OD/g grade IVD;

3. Rich types of modification: including special modified bases, thio modification, phosphoric acid modification, interstitial spacers, amino modification, thiol modification, biotin, Digoxin, fluorescent labeling, quenching group, electrochemical labeling, etc.

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