TBE is white to almost white instant granules. Each bag of this product can be prepared with 1L 1× TBE buffer solution. It is easy to operate and use. The main components of TBE are Tris, boric acid, and EDTA. The concentration of Tris in 1× TBE buffer is 89 mM, the concentration of boric acid is 89mM, and the concentration of EDTA is 2 mM. TBE is a common nucleic acid electrophoresis buffer in biology, mainly used for DNA agarose gel electrophoresis. TBE has strong buffering ability and is more effective in separating fragments smaller than 1kb, making it suitable for longer electrophoresis periods. When TBE is used for agarose gel, it is easy to cause high electroosmotic effect, and the gel extraction rate of DNA fragments is reduced due to the formation of noncovalently bound tetrahydroxy borate complex by interaction with agarose, so it is not recommended for the DNA fragments' gel extraction.