Fluorescence immunochromatography unlocks different tumor marker assays!
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The commonly used techniques for tumor marker detection include enzyme linked immunosorbent assay (ELISA), chemiluminescence assay (CLIA), etc.But if more detection technologies need to be expanded, more accurate real-time detection (POCT) can also be achieved through fluorescence immunochromatography.
DIA-UP can now provide a complete set of detection service solutions for tumor biomarkers on the fluorescence immunochromatography platform,包Including: total prostate specific antigen (TSA), alpha fetoprotein (AFP), Carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), etc.
Immunofluorescence chromatography technology is a new membrane detection technology based on antigen antibody specific immune response, which uses fluorescent substances to label antibodies for antigen localization. The use of fluorescence can further enhance the detection sensitivity. Compared to other immune detection technologies,The most significant feature is its higher accuracy and sensitivity, which is why it is more widely used in precise quantitative projects.
· Total Prostate Specific Antigen Determination Fluorescent Plate (tPSA)
The increase of serum T-PSA generally indicates the presence of prostate diseases (Prostatitis, benign hyperplasia or cancer), which can be used for screening and early diagnosis of prostate cancer in high-risk groups, monitoring the condition and efficacy of prostate cancer patients or patients receiving hormone therapy. The positive critical value for serum T-PSA quantification is greater than 10 μ G/L, the diagnostic specificity of prostate cancer reaches 90% to 97%, which has significant clinical significance in assisting in the diagnosis of prostate cancer.
· Alpha fetoprotein assay fluorescent plate (AFP)
The full name of alpha fetoprotein is alpha fetoprotein, which belongs to a glycoprotein with a molecular weight of about 70KD, and is mainly synthesized and secreted by the Yolk sac and liver. The diagnostic and treatment guidelines for primary liver cancer specify that serum alpha fetoprotein (AFP) is a commonly used and important indicator for the diagnosis and efficacy testing of liver cancer.
· Carcinoembryonic antigen assay fluorescent plate (CEA)
Carcinoembryonic antigen (CEA) is an acidic glycoprotein with human embryonic antigen characteristics, which exists on the surface of cancer cells differentiated from Endoderm cells. Carcinoembryonic antigen still has high clinical application value in the differential diagnosis, condition monitoring, preoperative evaluation, efficacy evaluation, recurrence monitoring and other aspects of malignant tumors.
· Carbohydrate Antigen 125 Determination Fluorescent Plate (CA125)
The determination of carbohydrate antigen 125 (CA125) has great value in the diagnosis and differential diagnosis of ovarian cancer and other gynecological diseases. Combining gynecological examination, imaging, pathology, and other comprehensive analysis can achieve the goal of early detection and treatment.
(Excitation 365nm, emission 610nm)
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DIA-UP BIOTECH
BIOTECH
DIA-UP was established in 2012, with a professional technical research and development team with over 10 years of experience, and has won multiple invention patents. The company has built a research and development platform for in vitro diagnostic materials (covering 10 major product systems, including primer and probe synthesis, nucleic acid molecular detection materials, immune reagent materials, biochemical reagent materials, hemagglutination reagent materials, fluorescent immunochromatography POCT large plate, biochemical reagent large package, hemagglutination reagent large package, calibration quality control products, etc.), automated high-throughput DNA reading and writing platform, RNA Intelligent design and synthesis platform, protein antibody preparation platform Five core technology platforms, including the supply platform for scientific research reagents and consumables.
DIA-UP adopts a 100000/10000 level purification workshop for product production and packaging, strictly adhering to the ISO13485:2016 quality management system standards, adhering to the development concept of 'craftsmanship quality, customer achievement', and committed to providing high-quality products and services to customers in the field of in vitro diagnosis and scientific research.
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